Chelsea crumbled as Roma moved to the top of Champions League Group C with a 3-0 victory at Stadio Olimpico on Tuesday night.
Stephan El Shaarawy scored after 38 seconds and pounced on an Antonio Rudiger error to make it 2-0 after 36 minutes.
Diego Perotti struck a fine third after 63 minutes and there would be no Chelsea comeback this time as Roma moved on to eight points, one more than the Blues.
A win in Antonio Conte’s first match in Italy as Blues boss would have seen Chelsea advance to the knockout stages.
Now Conte’s men need points at Azerbaijan’s Qarabag before the final group clash with Atletico Madrid.
Roma XI: Alisson, Florenzi, Fazio, Jesus, Kolarov, Nainggolan, De Rossi, Strootman, El Shaarawy, Dzeko, Perotti.
Chelsea XI: Courtois, Luiz, Rudiger, Cahill, Azpilicueta, Fabregas, Bakayoko, Alonso, Pedro, Morata, Hazard.